The global g-protein coupled receptors market size is expected to reach USD 6.10 billion by 2032, according to a new study by Polaris Market Research. The report “G-Protein Coupled Receptors Market Share, Size, Trends, Industry Analysis Report, By Product (Cell Lines, Detection Kits, Cell Culture Reagents, Ligands), By Assay Type, By Application, By Region, And Segment Forecasts, 2023 - 2032” gives a detailed insight into current market dynamics and provides analysis on future market growth.

The increasing adoption of High-Throughput Screening (HTS) technology, known for its speed and accuracy, by pharmaceutical companies is anticipated to boost the market growth for G-protein coupled receptor (GPCR)-targeted therapeutics. HTS is applied in G-protein coupled receptor cell-based assays, aiding various drug development initiatives. This technology allows pharmaceutical firms to analyze many compounds efficiently in a short period. In the context of GPCR research, HTS facilitates the screening of compounds against GPCR targets, enabling researchers to identify potential therapeutic candidates quickly and accurately.

As per a November 2021 article from PubMed Central, the human genome comprises over 700 genes forming the GPCRs, constituting the largest family of cell surface signaling receptors. These receptors play a crucial role in diverse physiological functions, including sensory modulation and hormonal responses. Recent studies have revealed the impact of GPCR signaling on various aspects of cancer biology, including invasion, migration, and vascular remodeling. GPCRs are significant in numerous cancer types, influencing cancer cell proliferation, angiogenesis, invasion, and metastasis.

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G-protein coupled receptors (GPCRs) possess distinct structural and functional characteristics that enable them to mediate physiological responses to hormones, stimulants, and neurotransmitters. This unique capability makes them promising therapeutic targets for a wide range of diseases. Recent advancements in the field of structural biology have offered valuable insights into the molecular mechanisms governing the activation and function of these receptors.

These insights have spurred significant interest among pharmaceutical companies, leading them to invest efforts in the development of therapeutics targeting G-protein coupled receptors. By understanding the intricate structural details and signaling pathways associated with GPCRs, researchers can design drugs that specifically modulate these receptors' activities. Pharmaceutical companies are exploring these avenues to create targeted therapies tailored to various disorders, capitalizing on the diverse roles GPCRs play in physiological responses. These ongoing research efforts hold the potential to revolutionize treatments for multiple diseases by harnessing the intricate mechanisms of G-protein coupled receptors.

G-Protein Coupled Receptors Market Report Highlights

• cAMP assays segment held the largest share, as these are extensively used in the HTS platforms
• Cancer research segment dominated the market due to growing cancer cases, investments in oncology research projects
• North America dominated the market, as the region has a huge network of industry-academia collaboration with funding support from the federal government
• The key market players include Thermo Fisher, Eurofins Scientific, QIAGEN, WuXi AppTec, Promega Corp., and Abcam

Polaris Market Research has segmented the g-protein coupled receptors market report based on product, assay type, application, and region:

G-Protein Coupled Receptors, Product Outlook (Revenue - USD Billion, 2019 - 2032)

• Cell Lines
• Detection Kits
• Cell Culture Reagents
• Ligands

G-Protein Coupled Receptors, Assay Type Outlook (Revenue - USD Billion, 2019 - 2032)

• cAMP Functional Assays
• Calcium Functional Assays
• β-Arrestin Functional Assays
• Radioligand Binding GTPγS Functional Assays
• Internalization Assays
• Trafficking Assays
• Others

G-Protein Coupled Receptors, Application Outlook (Revenue - USD Billion, 2019 - 2032)

• Cancer Research
• CNS Research
• Metabolic Research
• Cardiovascular Research
• Respiratory Research
• Inflammation Research
• Others

G-Protein Coupled Receptors, Regional Outlook (Revenue - USD Billion, 2019 - 2032)

• North America

• U.S.
• Canada

• Europe

• Germany
• UK
• France
• Italy
• Spain
• Russia
• Netherlands

• Asia Pacific

• China
• India
• Japan
• South Korea
• Indonesia
• Malaysia

• Latin America

• Argentina
• Brazil
• Mexico

• Middle East Africa

• UAE
• Saudi Arabia
• Israel
• South Africa